Thank you to everyone who helped and came to see us for all their expertise and enthusiasm.
The BSI's big nose
Karsten Koehler with a bag the 'snot' will be mixed and taken home in.
Andrew Chan and Hannah Siddle
Last minute adjustments to the ingeneous giant cytotoxic T-cell- Yvonne Hackmann
blowing up target cells... Andrew Munro
Karen Angus makes cytotoxic T cells taste sweet
Also, Suzanne Turner made blood out of sweets (but I didn't get a picture)
Have you got any pictures of the Cambridge Science Festival we could put on here?
from 10:00 AM to 06:00 PM
The Babraham Institute will be hosting a one day meeting on Monday 23rd June 2014 from 10am – 6pm on ‘PI3-Kinases in Immunity, Inflammation and Infection’. This event is open to all research scientists, PhD students, postdocs and PIs with an interest in PI3-kinase research.
We are pleased to announce that a plenary lecture will be given by Dr Roger Williams from the MRC-Laboratory of Molecular Biology on ‘The Structure and Function of PI3-Kinase Isoforms’.
The plenary lecture will be followed by a series of short talks selected from submitted abstracts. Registration is £20 and includes tea, coffee, lunch and weather permitting a BBQ with cash bar.
Places are limited so register now: http://bit.ly/1i6UKGy
Michael P. Weekes, Peter Tomasec, Edward L. Huttlin, Ceri A. Fielding, David Nusinow, Richard J. Stanton, Eddie C.Y. Wang, Rebecca Aicheler,Isa Murrell, Gavin W.G. Wilkinson, Paul J. Lehner, Steven P. Gygi
Cell 157, Issue 6, p1460–1472, 5 June 2014
Katherine Anagnostou , Sabita Islam, Yvonne King , Loraine Foley, Laura Pasea, Simon Bond , Chris Palmer , John Deighton , Pamela Ewan, Andrew Clark Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial The Lancet, Early Online Publication, 30 January 2014
Murchison EP, Wedge DC, Alexandrov LB, Fu B, Martincorena I, Ning Z, Tubio JM, Werner EI, Allen J, De Nardi AB, Donelan EM, Marino G, Fassati A, Campbell PJ, Yang F, Burt A, Weiss RA, Stratton MR. Transmissible dog cancer genome reveals the origin and history of an ancient cell lineage. Science. 2014 Jan 24;343(6169):437-40.
Immunotherapy in pancreatic cancer:
Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI,Tuveson DA, Fearon DT.Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proc Natl Acad Sci U S A;110(50):20212-7
The immunological synapse under hedgehog control in Science:
Predicting different outcomes after diagnosos in Cell:
Mutation in rare diseases that predisposes to respiratory infection in Science:
Ivan Angulo, Oscar Vadas,Fabien Garçon,Edward Banham-Hall Vincent Plagnol, Timothy R. Leahy, Helen Baxendale, Tanya Coulter, James Curtis, Changxin Wu, Katherine Blake-Palmer, Olga Perisic, Deborah Smyth9 Mailis Maes, Christine Fiddler, Jatinder Juss, Deirdre Cilliers, Gašper Markelj, Anita Chandra, George Farmer, Anna Kielkowska, Jonathan Clark, Sven Kracker, Marianne Debré, Capucine Picard, Isabelle Pellier, Nada Jabado, James A. Morris, Gabriela Barcenas-Morales, Alain Fischer, Len Stephens, Phillip Hawkins, Jeffrey C. Barrett,20 Mario Abinun,5 Menna Clatworthy, Anne Durandy, Rainer Doffinger, Edwin R. Chilvers, Andrew J. Cant, Dinakantha Kumararatne, Klaus Okkenhaug, Roger L. Williams, Alison Condliffe, Sergey Nejentsev Phosphoinositide 3-Kinase Gene Mutation Predisposes to Respiratory Infection and Airway Damage October 2013; 10.1126/science.1243292
Crohn's disease as a specific disorder of Paneth cells in Nature:
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS. Paneth cells as a site of origin for intestinal inflammation.Nature. 2013 Nov 14;503(7475):272-6.