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Science Festival 2014

Some pictures from the Cambridge Science Festival 2014 taken on Saturday 15 March at the Pathology Department and on Sunday 23rd March at the Clinical School

Thank you to everyone who helped and came to see us for all their expertise and enthusiasm.

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The BSI's big nose

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alice

beccy nele

anna

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snot colour chart

Science Festival 13

Lots of immunology as part of the 'Cosmos of your body' and 'Why Snot' exhibits in the Department of Pathology at the Cambridge Science Festival

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Karsten Koehler with a bag the 'snot' will be mixed and taken home in.

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Andrew Chan and Hannah Siddle

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Last minute adjustments to the ingeneous giant cytotoxic T-cell- Yvonne Hackmann

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blowing up target cells... Andrew Munro

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Karen Angus makes cytotoxic T cells taste sweet

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Alice Denton and Michelle Linterman in full swing with snot

Also, Suzanne Turner made blood out of sweets (but I didn't get a picture)

Have you got any pictures of the Cambridge Science Festival we could put on here?

PI3-Kinases in Immunity, Inflammation and Infection

Event details

When

Jun 23, 2014
from 10:00 AM to 06:00 PM

Where

The Babraham Institute

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The Babraham Institute will be hosting a one day meeting on Monday 23rd June 2014 from 10am – 6pm on ‘PI3-Kinases in Immunity, Inflammation and Infection’.  This event is open to all research scientists, PhD students, postdocs and PIs with an interest in PI3-kinase research.

We are pleased to announce that a plenary lecture will be given by Dr Roger Williams from the MRC-Laboratory of Molecular Biology on ‘The Structure and Function of PI3-Kinase Isoforms’.

The plenary lecture will be followed by a series of short talks selected from submitted abstracts.  Registration is £20 and includes tea, coffee, lunch and weather permitting a BBQ with cash bar.

Places are limited so register now: http://bit.ly/1i6UKGy

More information about this event…

Pictures of Cambridge Immunology Forum 2014

Event details

When

Oct 07, 2014
from 05:55 PM to 05:55 PM

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cerirobertspicture by Ceri Roberts

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And the poster winners were:

Rebecca Newman, Babraham (1st prize, PhD)

Wim Pierson, Babraham  (runner up, PhD)

Maike de la Roche, CIMR (1st prize, postdocs)

Alison Galloway, Babraham  (runner up, postdocs)

High Profile Publications

 

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

Michael P. Weekes, Peter TomasecEdward L. HuttlinCeri A. Fielding, David NusinowRichard J. StantonEddie C.Y. WangRebecca Aicheler,Isa MurrellGavin W.G. WilkinsonPaul J. LehnerSteven P. Gygi

Cell 157, Issue 6, p1460–1472, 5 June 2014

 

A new therapy for peanut allergy has been successful in the majority of children who took part in a clinical trial:

Katherine Anagnostou , Sabita Islam, Yvonne King , Loraine Foley, Laura Pasea, Simon Bond , Chris Palmer , John Deighton , Pamela Ewan, Andrew Clark Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial The Lancet, Early Online Publication, 30 January 2014

11,000-year-old living dog cancer reveals its secrets:

Murchison EP, Wedge DC, Alexandrov LB, Fu B, Martincorena I, Ning Z, Tubio JM, Werner EI, Allen J, De Nardi AB, Donelan EM, Marino G, Fassati A, Campbell PJ, Yang F, Burt A, Weiss RA, Stratton MR. Transmissible dog cancer genome reveals the origin and history of an ancient cell lineage. Science. 2014 Jan 24;343(6169):437-40. 

Immunotherapy in pancreatic cancer:

Feig C, Jones JO, Kraman M, Wells RJ, Deonarine A, Chan DS, Connell CM, Roberts EW, Zhao Q, Caballero OL, Teichmann SA, Janowitz T, Jodrell DI,Tuveson DA, Fearon DT.Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proc Natl Acad Sci U S A;110(50):20212-7

 

The immunological synapse under hedgehog control in Science:

Predicting different outcomes after diagnosos in Cell:

Lee JC, Espéli M, Anderson CA, Linterman MA, Pocock JM, Williams NJ, Roberts R, Viatte S, Fu B, Peshu N, Hien TT, Phu NH, Wesley E, Edwards C, Ahmad T, Mansfield JC, Gearry R, Dunstan S, Williams TN, Barton A, Vinuesa CG; UK IBD Genetics Consortium, Parkes M, Lyons PA, Smith KG. Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway. Cell. 2013 Sep 26;155(1):57-69.

 

Mutation in rare diseases that predisposes to respiratory infection in Science:

Ivan Angulo, Oscar Vadas,Fabien Garçon,Edward Banham-Hall Vincent Plagnol, Timothy R. Leahy, Helen Baxendale, Tanya Coulter, James Curtis, Changxin Wu, Katherine Blake-Palmer, Olga Perisic, Deborah Smyth9 Mailis Maes, Christine Fiddler, Jatinder Juss, Deirdre Cilliers, Gašper Markelj, Anita Chandra, George Farmer, Anna Kielkowska, Jonathan Clark, Sven Kracker, Marianne Debré, Capucine Picard, Isabelle Pellier, Nada Jabado, James A. Morris, Gabriela Barcenas-Morales, Alain Fischer, Len Stephens, Phillip Hawkins, Jeffrey C. Barrett,20 Mario Abinun,5 Menna Clatworthy, Anne Durandy, Rainer Doffinger, Edwin R. Chilvers, Andrew J. Cant, Dinakantha Kumararatne, Klaus Okkenhaug, Roger L. Williams, Alison Condliffe, Sergey Nejentsev Phosphoinositide 3-Kinase Gene Mutation Predisposes to Respiratory Infection and Airway Damage  October 2013; 10.1126/science.1243292

 

 Crohn's disease as a specific disorder of Paneth cells in Nature:

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