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Interaction of a human T regulatory cell and dendritic cell involving the type 1 diabetes susceptibility molecule, CTLA-4. Yellow = B7.1+CTLA4. Photograph reproduced with kind permission from Paul MacAry

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Kidneys from old autoimmune prone mice have been stained for laminin (red) to highlight the tubular organisation and for IgG (green). Immune complex deposition in the glomeruli and infiltrating plasma cells in the tubuloinsterstitium can be observed. by Marion Espeli

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trowsdale

Using a novel, high-throughput copy number assay for KIR typing we have shown that there are many unconventional arrangements of KIR genes. This assay can be used to understand the relationship between MHC class I molecules, their receptors and disease conditions, including autoimmunity, infection, matching in stem cell transplants for leukaemia and disorders of pregnancy. John Trowsdale

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Lymphatic vessels

Lymphatic vessels in skin labelled with LYVE-1 (green), CD31 (red), DAPI (blue)

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Crypt abscess in the intestinal mucosa as a consequence of unresolved endoplasmic reticulum stress due to hypomorphic XBP1 function (H&E staining

 
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antibody structure by Michael Clark

C6 does not inhibit the translocation or activation of NF-kB. (A) HEK293 cells were grown on coverslips and transfected with

 
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bladder Clatworthy

confocal imaging of bladder dendritic cells

dendritic cells in the kidney

Two photon imaging of dendritic cells in the kidney using CD11cEYFP mice.

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renal tubular cells

 
Doug Fearon

A confocal image of EGFP-positive stromal cells in a B16 melanoma that express fibroblast activation protein-alpha and that mediate local immunosuppression.

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antibody ss

 
leo james

 
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IRAK

 
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Cartoon example

 
Veldhoen Immuno 2 2 11

 
intracellular bacterium

intracellular bacterium

IL 33CIT lung slices

 
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hpv

 
stanley sterling

 
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drinks

 
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Thijn Brummelkamp

 
Viral Neutralization inside Infected Cells

 
Tamtsu Yoshimori

 
Sasha Tarakhovsky

 
SAMHD1 the Guardian of non dividing cells

 
Roche Lecture

 
Paul Lehner

 
Otto Haller

 
Organizers Paul Lehner & Felix Randow

 
Monsef Benkirane

 
Mechanistic Insights into Autophagy against Bacteria Invading Host Cells

 
Leo James

 
John MacMicking

 
INF inducible host Resistance Programs to Infection

 
HIV, TRIM5 and Innate Immunity Going under the Radar

 
Hijacking of the Cell's Epigenome by Influenza Virus

 
Haploid Genetic Screens in Human Cells to Identify Host Factors for Pathogens

 
Greg Towers

 
Felix Randow

 
Chair Menna Clatworthy

 
Chair Ken Smith

 
Chair Gillian Griffiths

 
Chair Geoff Smith

 
Autophagy in Host pathogen Interactions

 
Medimmune

Upcoming events

Emerging Viruses of Zoonotic and Veterinary Importance

Jul 24, 2017

Churchill College, Cambridge

Antibody Technologies and Therapeutics Conference

Sep 10, 2017

Monash University Conference Centre Prato , Italy

Exploring Human Host-Microbiome Interactions in Health and Disease

Sep 13, 2017

Wellcome Conference Centre, Hinxton

Upcoming events

The new Capella building- CITIID

See the home of CITIID being built in this fantastic time-lapse video. From basement to water tight in 17 months. The Capella building will be finished in 2018.

FCEs provide interdisciplinary training programmes for students, fellows and continuing education physicians through FOCIS assisted opportunities

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