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Dr Jason Ali

Dr Jason Ali

Wellcome Trust Clinical Research Training Fellow

Research Interests

Supervisor: Gavin Pettigrew 

My research focuses on allorecognition pathways in transplantation - the direct and indirect pathways. The aim is to characterise the longevity of these pathways and to understand if this knowledge may facilitate the development of novel immuno-regulatory therapies - such as with pathway and antigen specific regulatory T cells, which may help to prevent the development of chronic rejection, which is inevitable in clinical transplantation currently.


Funding: Wellcome Trust Clinical Research Training Fellowship


alloimmunity ; T-cell allorecognition ; alloantibody ; regulatory T cells ; direct and indirect allorecognition, ; allorecognition

Key Publications

Ali JM, Bolton EM, Bradley JA, Pettigrew GJ. Allorecognition pathways in transplant rejection and tolerance. Transplantation. 2013 Oct 27;96(8):681-8 PMID 23715047