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Dr Seth Thomas Scanlon

Research Interests

Seth is an Associate Editor at Science. His areas of responsibility include immunology, hematology, and host–pathogen interactions. Hailing from Philadelphia, USA, his undergraduate work on lung surfactant proteins was with Michael F. Beers at the University of Pennsylvania. This was followed by a doctorate at the University of Chicago under the supervision of Albert Bendelac on the role of semi-invariant NKT cells in asthma. He then moved to Cambridge, UK, where he studied type 2 innate lymphoid cell (ILC2) regulation and trafficking in Andrew N.J. McKenzie’s group at the MRC Laboratory of Molecular Biology. This was followed by a six-month stint in Amy E. Saunders’ lab at the University of Manchester. Seth has been the immunology editor at Science since June 2017 and now divides his time between his home office in Leeds, UK and the AAAS International office in Cambridge, UK.

Topics

  • Immunology
  • Publishing
  • Host–pathogen interactions
  • Hematology
  • Editing
  • Journals

Key Publications

Halim TY, Hwang YY, Scanlon ST, Zaghouani H, Garbi N, Fallon PG, McKenzie AN. Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses. Nat Immunol. 2016 Jan;17(1):57-64

Oliphant CJ, Hwang YY, Walker JA, Salimi M, Wong SH, Brewer JM, Englezakis A, Barlow JL, Hams E, Scanlon ST, Ogg GS, Fallon PG, McKenzie AN.MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4(+) T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion Immunity. 2014 Aug 21;41(2):283-95.

Salimi M, Barlow JL, Saunders SP, Xue L, Gutowska-Owsiak D, Wang X, Huang LC, Johnson D, Scanlon ST, McKenzie AN, Fallon PG, Ogg GS. A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med. 2013 Dec 9.

Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
Nature. 2012 Nov 22;491(7425):618-21 

Scanlon ST, Thomas SY, Ferreira CM, Bai L, Krausz T, Savage PB, Bendelac A. Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation. J Exp Med. 2011 Sep 26;208(10):2113-24.

Thomas SY, Scanlon ST, Griewank KG, Constantinides MG, Savage AK, Barr KA, Meng F, Luster AD, Bendelac A. PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions.
J Exp Med. 2011 Jun 6;208(6):1179-88.