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Jennifer Hill

Research Interests

Supervisor: Professor Gordon Dougan

My research investigates the interaction between the host and bacterial pathogens at the mucosal surface of the colon. I use knock-out mice to investigate the function of host genes at this interface, and my work includes studying the host response to infections with the mouse-restricted pathogen Citrobacter rodentium and also Salmonella Typhimurium.

Keywords

DNA sensing pathways ; interferons ; macrophages ; proteomics ; Citrobacter rodentium ; innate immunity ; EPEC ; metabolomics ; salmonella ; mucosal immunity

Key Publications

Clare S, John V, Walker AW, Hill JL, Abreu-Goodger C, Hale C, Goulding D, Lawley TD, Mastroeni P, Frankel G, Enright AJ, Vigorito E, Dougan G. Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect Immun. 2013 Mar; 81(3):723-32. 

Scott KA, Porter SL, Bagg EA, Hamer R, Hill JL, Wilkinson DA, Armitage JP. Specificity of localization and phosphotransfer in the CheA proteins of Rhodobacter sphaeroides. Mol Microbiol. 2010 Apr; 76(2):318-30.