Submitted by Dr Tennie Videler on Fri, 13/02/2015 - 15:59
Dr Eoin McKinney: Tired of relapsing: manipulating T-cell exhaustion as a treatment for autoimmune disease
Eoin is a nephrologist with an interest in the pathways driving and marking severe, relapsing autoimmune disease. He is using his Fellowship to explore parallel ways in which the immune response deals with persistent infection and persistent self-antigen during a number of relapsing autoimmune and inflammatory diseases. He is using a cellular model of T-cell differentiation that recreates changes seen in patients with relapsing disease. Using a combination of bioinformatics, virology and cellular immunology techniques, Eoin aims to modify those changes and to identify novel targeted treatment strategies for patients.
