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Cambridge Immunology Network

 

Research

Supervisor: Professor Hill Gaston

My research interests are currently focused on immune regulation, specifically the role of innate immunity in inflammatory conditions. I am currently undertaking a PhD at the University of Cambridge within this field.

I graduated from the University of Leeds in 2006 with a BSc in Medical Sciences, and subsequently work at GlaxoSmithKline investigating novel therapies for steroid-resistant asthma. I then completed my Masters degree in Immunology at Imperial College London in 2010 where my work was focused on investigating effects of cytokines on memory CD8+ T cells.

I then joined King’s College London in October 2010 where I investigated the clinical potential of regulatory T cells; firstly in type 1 diabetes, and subsequently with regard to developing protocols for the safe and reproducible expansion of gut-tropic Tregs for use in Inflammatory Bowel Disease.

Publications

Key publications: 
Byrne SM, Aucher A, Alyahya S, Elder M, Olson ST, Davis DM, Ashton-Rickardt PG.  Cathepsin B controls the persistence of memory CD8+ T lymphocytes. J Immunol. 2012 Aug 1;189(3):1133-43. doi: 10.4049/jimmunol.1003406. Epub 2012 Jun 27.
 
 Matthew  Elder
Not available for consultancy

Affiliations

Classifications: 
Departments and institutes: 
Person keywords: 
western blot
RT-PCR
innate immunity
regulatory T cells
sterile tissue culture
primary cell line generation
FACS
adaptive immunity
ELISA's
ELIspot
memory cells