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Project: Molecular target identification in Sjogrens Syndrome, Postdoctoral fellow based in GSK, Stevenage, UK

GSK, Stevenage


 Prof. Timothy Radstake, MD, PhD, who is on secondment at GSK from University Medical Center Utrecht where he is Professor of Translational Immunology and Director of Utrecht Infection and Immunity FOCIS center of Excellence, 

has a vacancy for a postdoctoral fellow based in Stevenage, UK 

Project: Molecular target identification in Sjogrens Syndrome 

We are seeking exceptional applicants with practical and theoretical knowledge in immunology and molecular biology. The current project builds on a systems biology approach we have performed recently aimed at the identification of causative molecular pathways underlying immune mediated diseases (Sjogrens disease). The candidate for this position will be responsible for testing potential candidate molecules. Candidates should be interested in a team-oriented research and have a proven track-record on implementing knowledge derived from molecular biology to better understand pathogenic molecular mechanisms and identify key therapeutic targets for precision medicine. We want an independent, creative, innovative and well-organized person with excellent cooperative skills. 

Minimum Requirements: 

- Degree from an accredited college or university in molecular biology. 

- PhD in molecular biology or related fields. 

- Deep knowledge on setting up, optimizing and the execution of organotypic (complex) in vitro & in vivo models for Proof of Concept (PoC) studies. 

- Capability to plan and execute experimental models (mice / rat) for PoC. 

- Basic knowledge in statistics 

- Excellent communication and organizational skills 


Preferred Requirements: 

- Experience with cell and molecular biology, protein biochemistry, cell biology or flow cytometry. 

- Background in immunology 

- Skills/experience in analyzing high-throughput data 

- Skills/experience in tools for the biological interpretation of high-throughput data, as pathways/Go-term enrichment. 


To apply, please email Prof. Radstake: 

Immunology Catalyst postdoctoral training programme 

GSK has launched a novel research collaboration model – the Immunology Catalyst – designed to drive major breakthroughs in applied immunology and broaden scientific insight. 

What is the Immunology Catalyst? 

We have selected leading academic immunologists to join us at our world class R&D facility in Stevenage, UK, where they will work alongside GSK’s scientists while pursuing their own independent research programmes focused on basic immunology questions. They will have access to GSK’s technologies and research tools and, by connecting with our scientists, have the opportunity to expand their knowledge of drug discovery and translational research. Paul-Peter Tak, SVP immunoinflammation therapy area, GSK, is the programme sponsor. The Immunology Catalyst members are also supported by a network of leading immunologists at GSK and an external immunology board of world class immunologists including Professors Vijay Kuchroo, Jerry Nepom, Luke O’Neill, Fiona Powrie, Hergen Spits, Isaac Chiu, Erika Pearce, Chris Buckley, Michael Brenner, Lisa Coussens and Bali Pulendran. 

What will the programme be like & what will I learn? 

As a postdoctoral fellow in the Immunology Catalyst, you will have a world class academic immunologist as a mentor who will be focused on providing a comprehensive training programme and is expected to nurture skills that will enable you to become an independent scientific investigator. You will have the opportunity to author publications in high-impact scientific journals while rounding out your training with a deeper understanding of translation of drug discovery & development to medicines of value for patients. 

At the start of your post-doc, you’ll work with your supervisor to design a programme of research with mutually agreed timelines, milestones, objectives, accountability, and duration (2 years). During your time you will have access to the expertise of GSK’s Immunology Network including the other academic immunologists on sabbatical, leading GSK immunologists and the external immunology board in addition to your direct supervisor. You will also have access to the extensive R&D engine including our: tools, technologies, libraries, samples, people, knowledge base, R&D events, and post-doc community events. 

You will have unrivalled experience of both academic and industry settings, exposure to industry leading research, high levels of innovation, and creativity, and also develop the ability to work in an international scientific environment. This training will prepare you well for a career in academia, industry, a regulatory or non-profit healthcare organisation.

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