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Cambridge Immunology Network

 

Cambridge leads national drug trial to prevent deaths after COVID-19 patients leave hospital

25 March 2021

A UK-wide study is being launched to reduce the number of people who die in the months following a stay in hospital with COVID-19. The clinical trial - named HEAL-COVID - also aims to cut the number of patients being readmitted to hospital with complications as a result of having COVID. Read the original article here>

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Cambridge leads trial to see if tapeworm drug can boost protection from COVID-19 among vulnerable

23 March 2021

UK researchers are launching a clinical trial to investigate if the drug niclosamide, usually used to treat tapeworms, can prevent COVID-19 infection in vulnerable, high risk kidney patients and reduce the number of people who become seriously ill or die from it. Read the original article here>

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Hunting for COVID-19 Variants

22 March 2021

The story behind the UK's world-leading SARS-CoV-2 genomics capability. For years, Professor Sharon Peacock has been using cutting-edge genome sequencing to track outbreaks of infectious diseases and to better understand how pathogens spread and evolve. When SARS-CoV-2 emerged just over a year ago, she knew that her work...

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Changes can be detected in BRCA1 breast cells before they turn cancerous

9 March 2021

Researchers may have found the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear, according to a new study published today in the journal Nature Communications. Read the original article here>

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Diphtheria risks becoming ‘major global threat’ again as it evolves resistance to antimicrobials

8 March 2021

Diphtheria – a relatively easily-preventable infection – is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn researchers from the UK and India. Read the original article here>

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Genomics study identifies routes of transmission of coronavirus in care homes

3 March 2021

Genomic surveillance – using information about genetic differences between virus samples – can help identify how SARS-CoV-2 spreads in care home settings, whose residents are at particular risk, according to new research published today. Read the original article here>

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Single dose of Pfizer BioNTech vaccine reduces asymptomatic infections and potential for SARS-CoV-2 transmission

26 February 2021

New data from Addenbrooke's Hospital in Cambridge suggests that a single dose of the Pfizer BioNTech vaccine can reduce by 75% the number of asymptomatic SARS-CoV-2 infections. This implies that the vaccine could significantly reduce the risk of transmission of the virus from people who are asymptomatic, as well as...

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Scientists launch a pre-emptive strike on deadly post-transplant infection

24 February 2021

A potential new treatment to protect immunosuppressed patients from human cytomegalovirus (HCMV) has been discovered by scientists at the University of Cambridge. Their study shows that certain epigenetic inhibitors expose and help to destroy dormant HCMV infections, which often reactivate to cause serious illness and...

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Can a tapeworm drug boost protection from Covid-19 for high-risk kidney patients?

23 February 2021

UK researchers are launching a clinical trial to investigate if the drug niclosamide, usually used to treat tapeworms, can prevent Covid-19 infection in vulnerable, high-risk kidney patients and reduce the number of people who become seriously ill or die from it. Read the original article here>

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Q&A with Sharon Peacock, coronavirus variant hunter

22 February 2021

The UK is a world leader in sequencing SARS-CoV-2, the virus that causes COVID-19. Of all the coronavirus genomes that have been sequenced in the world, nearly half have been sequenced by COVID-19 Genomics UK Consortium (Cog-UK). The consortium began life on March 4 when Sharon Peacock, a professor of public health and...

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