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Immunotherapy - Cancer cure?

last modified Feb 17, 2016 03:31 PM
The researchers genetically modified the t-cells to engineer a new targeting mechanism - chimeric antigen receptors - to target acute lymphoblastic leukaemia.

The early stage trials in today’s reports involved patients with different types of blood cancer – including acute lymphoblastic leukaemiachronic lymphocyte leukaemia and non-Hodgkin lymphoma. While these are often very treatable forms of cancer, the patients on these trials had diseases that had become resistant to all other treatments.

Many media reports focused on the patients with acute lymphoblastic leukaemia, more than nine in 10 of whom are reported to have entered remission following the immune cell therapy.

The researchers are also reported to have seen similarly impressive responses in around half of patients with the other blood cancers too.

These are indeed truly impressive results.

But these responses – where patients see their symptoms disappear – don’t necessarily mean a patient has been cured. And without a scientific paper to back up the reports, we don’t yet have the full details on these responses rates – notably exactly how they were measured.

 

More on this story can be found at the CRUK site here.

Upcoming events

Cambridge Parasitic and Neglected Tropical Diseases Network Day

Dec 13, 2018

Lecture Theatre, Department of Pathology, Tennis Court Road, Cambridge CB2 1QP

Immunogenomics of Disease: Accelerating to Patient Benefit

Feb 05, 2019

Wellcome Genome Campus, UK

Upcoming events

The new Capella building- CITIID

See the home of CITIID being built in this fantastic time-lapse video. From basement to water tight in 17 months. The Capella building will be finished in 2018.

Fibroblast

‘Fibroblast’ has been developed from a conversation between Harold Offeh and Dr Alice Denton, a scientist based at the Babraham Institute and a member of the Cambridge Immunology Network. Offeh was particularly interested in the character and roles played by particular cells in the immune system, as well as the immune system’s role as a primary source of protection and care. The film takes as a starting point microscopic images of broblast cells, an area of research for Dr Denton.

FCEs provide interdisciplinary training programmes for students, fellows and continuing education physicians through FOCIS assisted opportunities

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