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Andres Floto et al repurpose anticonvulsants as tuberculosis drug

last modified Dec 30, 2014 12:46 PM
Functional drug screening reveals anticonvulsants as enhancers of mTOR‐independent autophagic killing of Mycobacterium tuberculosis through inositol depletion

Functional drug screening reveals anticonvulsants as enhancers of
mTOR‐independent autophagic killing of Mycobacterium tuberculosis through
inositol depletion


Carbamazepine reveals a novel mechanism of mTOR‐independent control of
autophagy that may be manipulated pharmacologically and provides proof of
principle that therapeutic autophagy stimulation can be an effective
strategy to treat multidrug‐resistant tuberculosis.

The new Jeffrey Cheah Biomedical Centre - CITIID

See the home of CITIID being built in this fantastic time-lapse video. From basement to water tight in 17 months. The Jeffrey Cheah Bimedical Centre is now complete and home to the Cambridge Immunology Network Coordinator.

Fibroblast

‘Fibroblast’ has been developed from a conversation between Harold Offeh and Dr Alice Denton, a scientist based at the Babraham Institute and a member of the Cambridge Immunology Network. Offeh was particularly interested in the character and roles played by particular cells in the immune system, as well as the immune system’s role as a primary source of protection and care. The film takes as a starting point microscopic images of broblast cells, an area of research for Dr Denton.

FCEs provide interdisciplinary training programmes for students, fellows and continuing education physicians through FOCIS assisted opportunities

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