skip to primary navigationskip to content
 

Dr Guillaume Bidault

Research Interests

Obesity is a chronic inflammatory disease characterized by adipose tissue infiltration with macrophages contributing to the metabolic and cardiovascular complications of obesity. My main area of research concerns the modulation of adipose tissue macrophages phenotype by their lipidome. More specifically, my research will focus on fatty acid signalling and its impact on their polarization status.

Topics

  • obesity

Key Publications

Guénantin AC, Briand N, Bidault G, Afonso P, Béréziat V, Vatier C, Lascols O, Caron-Debarle M, Capeau J, Vigouroux C. Nuclear envelope-related lipodystrophies. Semin Cell Dev Biol. 2014 May;29:148-57. PMID: 24384368

Vatier C, Bidault G, Briand N, Guénantin AC, Teyssières L, Lascols O, Capeau J, Vigouroux C. What the genetics of lipodystrophy can teach us about insulin resistance and diabetes. Curr Diab Rep. 2013 Dec;13(6):757-67. PMID: 24026869

Bidault G, Garcia M, Vantyghem MC, Ducluzeau PH, Morichon R, Thiyagarajah K, Moritz S, Capeau J, Vigouroux C, Béréziat V. Lipodystrophy-linked LMNA p.R482W mutation induces clinical early atherosclerosis and in vitro endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2162-71. PMID: 23846499

Bidault G, Vatier C, Capeau J, Vigouroux C, Béréziat V. LMNA-linked lipodystrophies: from altered fat distribution to cellular alterations. Biochem Soc Trans. 2011 Dec;39(6):1752-7. PMID: 22103520