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Cambridge Immunology Network



Key publications: 

Cavelti-Weder C*, Timper K*, Seelig E*, Keller C, Osranek M, Lässing U, Spohn G, Maurer P, Müller P, Jennings GT, Willers J, Saudan P, Donath MY, Bachmann MF. A non-human primate study and a randomized, double-blind, placebo-controlled phase I/II trial in patients with type 2 diabetes to determine the safety and antibody response of an interleukin-1β vaccine.  Mol Ther. 2015 Dec 21. doi: 10.1038/mt.2015.227.

Nordmann TM*, Seelig E*, Timper K*, Cordes M, Coslovsky M, Hanssen H, Schmidt-Trucksäss A, Donath MY. Muscle-Derived IL-6 Is Not Regulated by IL-1 during Exercise. A Double Blind, Placebo-Controlled, Randomized Crossover Study. PLoS One. 2015 Oct 8;10(10):e0139662. doi: 10.1371/journal.pone.0139662.

Timper K*, Seelig E*,  Tsakiris DA, Donath MY. Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus. J Diabetes Complications. 2015 Sep-Oct;29(7):955-60. doi: 10.1016/j.jdiacomp.2015.05.019.

Seelig E, Bilz S, Keller U, Meienberg F, Christ-Crain M. Concentrations of the Stress Hormone Copeptin increase upon Hypoglycaemia in Patients with Type 1 Diabetes dependent of Hypoglycaemia Awareness. PLoS One. 2013 Aug 30;8(8):e72876. doi: 10.1371/journal.pone.0072876.

Seelig E, Keller U, Klarhöfer M, Scheffler K, Brand S, Holsboer-Trachsler E, Hatzinger M, Bilz S. Neuroendocrine Regulation and Metabolism of Glucose and Lipids in Primary Chronic Insomnia: A Prospective Case-Control Study. PLoS One. 2013 Apr 12;8(4):e61780. doi: 10.1371/journal.pone.0061780.

*equally contributing

Not available for consultancy


Collaborator profiles: 
Person keywords: 
clinical immunology
CD4+ T regulatory cells