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Dr Jennifer Walker

Research Interests

My work focuses on the molecular regulation of type 2 immunity in asthma and the development of lymphoid lineages

Keywords

CD22 ; nuocytes ; FcgammaRII ; monoclonal antibodies

Topics

  • haemolytic anaemia
  • asthma

Collaborators

Key Publications

 

Oliphant CJ, Hwang YY, Walker JA, Salimi M, Wong SH, Brewer JM, Englezakis A, Barlow JL, Hams E, Scanlon ST, Ogg GS, Fallon PG, McKenzie AN.MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4(+) T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion Immunity. 2014 Aug 21;41(2):283-95.

Walker JA, McKenzie AN. Development and function of group 2 innate lymphoid cells. Curr Opin Immunol. 2013 Apr;25(2):148-55.

Walker JA, Barlow JL, McKenzie AN. Innate lymphoid cells - how did we miss them? Nat Rev Immunol. 2013 Jan 7.

Walker JA, Hall AM, Kotsopoulou E, Espeli M, Nitschke L, Barker RN, Lyons PA, Smith KG. Increased red cell turnover in a line of CD22-deficient mice is caused by Gpi1(c) : A model for hereditary haemolytic anaemia. Eur J Immunol. 2012 Dec;42(12):3212-22. 

Walker JA, McKenzie A. Innate lymphoid cells in the airways. Eur J Immunol. 2012 Jun;42(6):1368-74. 

Wong SH, Walker JA, Jolin HE, Drynan LF, Hams E, Camelo A, Barlow JL, Neill DR, Panova V, Koch U, Radtke F, Hardman CS, Hwang YY, Fallon PG, McKenzie AN. Transcription factor RORα is critical for nuocyte development. Nat Immunol. 2012 Jan 22;13(3):229-36.

Walker JA, Smith KG. Dependence of surface monoclonal antibody binding on dynamic changes in FcgammaRIIb expression. Immunology. 2008 Jul;124(3):412-8. doi: 10.1111/j.1365-2567.2007.02791.x. Epub 2008 Jan 24. Erratum in: Immunology. 2008 Jul;124(3):417.