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Dr Lori Turner

Research Interests

I am an immunologist with a background in host-pathogen interactions and microvesicles of both human and microbial origin.

My current research focuses on immune system function and dysregulation in various psychiatric disorders. Using multi-colour flow cytometry I am investigating alterations in immune cell subsets, with the ultimate goal of identifying peripheral biomarkers in patients with depression, Alzheimer’s disease, antibody-mediated encephalitis, chronic treatment resistant schizophrenia and treatment naïve psychosis. 

Keywords

T cells ; immunophenotyping ; biomarkers ; FACS ; translational immunology

Topics

  • psychiatry
  • schizophrenia
  • immunology
  • psychosis

Key Publications

Lorinda Turner, Judyta Praszkier, Melanie L. Hutton, David Steer, Georg Ramm, Maria Kaparakis-Liaskos, Richard L. Ferrero (2014). Increased outer membrane vesicle formation in a Helicobacter pylori tolB mutant. Helicobacter (accepted).

Aaron T Irving, Hitomi Mimuro, Thomas A Kufer, Camden Lo, Richard Wheeler, Lorinda J Turner, Belinda J Thomas, Christian Malosse, Michael P Gantier, Linda N Casillas, Bartholomew J Votta, John Bertin, Ivo G Boneca, Chihiro Sasakawa, Dana J Philpott, Richard L Ferrero, Maria Kaparakis-Liaskos (2014). The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling. Cell Host & Microbe. 15, 623–635.

Melanie L Hutton, Maria Kaparakis-Liaskos, Lorinda Turner, Ana Cardona, Terry Kwok, Richard L Ferrero (2010). Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells. Infection & Immunity. 78 (11), 4523-4531.