Dr Xi Chen

Transcriptional regulatory networks control cell fate decisions and cell cycle progression, both of which are key processes in the T helper cell compartment. T helper cells differentiate from a naïve resting state into a specific and proliferative state when they are presented with antigens. Transcription factors are the driving forces during this differentiation process. I am interested in utilising genomic technologies (ChIP-seq, RNA-seq etc.) to investigate how TFs control the T helper cell differentiation.