Marian Jones Evans

Research

Investigating the impact of hypoxia on cytotoxic T lymphocyte (CTL) function, including T cell receptor signalling pathways and regulation of effector cytokine production. Interested in the potential of modulating perturbed cell mechanisms to restore CTL function in hypoxic environments e.g. the tumour microenvironment.

Subject:

co-stimulatory molecules

cytokines

cytotoxic T cells (CTL)

Cytotoxicity

Granzyme

Hypoxia