Research
My main interests are in tissue-resident immunity and the impact of infection on tissue-resident immune cell subsets.
I am currently working on a project in Professor Menna Clatworthy's lab to determine the role of kidney-resident natural killer cells in health and disease.
Publications
ORCID: https://orcid.org/0000-0002-2058-4045
First authored papers
1. Bowyer et al J Exp Med 2020 “Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells” PMID: 32413101
2. Bowyer et al Front Immunol 2018 “CXCR3+ T follicular helper cells induced by co-administration of RTS,S/AS01B and viral-vectored vaccines are associated with reduced immunogenicity and efficacy against malaria” PMID: 30090099
3. Bowyer et al Vaccines 2018 “Activation-induced markers detect vaccine-specific CD4+ T cell responses not measured by assays conventionally used in clinical trials” PMID: 30065162
Key Co-authored papers:
1. Gola et al. Sci Transl Med 2018 - Prime and target immunization protects against liver-stage malaria in mice.
2. Obeng-Adjei et al. PLoS Pathog 2017 - Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells.
3. Ewer et al. N Engl J Med 2016 - A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA.
4. Ogwang et al. Sci Transl Med 2015 - Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults."