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Themes of Research

Immunologists in Cambridge work across a wide range of research areas. For further information on the main research themes given below, click on the theme. People who work within a theme are listed below it. The research of many cuts across multiple themes.

Autoimmunity and inflammation

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Investigating the causes of excessive and aberrant immune responses which result in inflammation and autoimmune disease 







Cellular immune responses and immune regulationIL 33CIT lung slices

Immune responses involve the activation and coordination of specialized cells and mediators. We aim to unravel these tightly regulated and complex interactions







Clinical and translational immunology

Crypt abscess in the intestinal mucosa as a consequence of unresolved endoplasmic reticulum stress due to hypomorphic XBP1 function (H&E staining

Translating basic immunological discoveries into clinically useful tools








Immunity and host defencesGriffiths

Host responses fight microbial infection and disease and understanding these will optimise vaccination 









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Innate immunity

Innate immunity is critical in recognition of and response to pathogens and tumours, including directing the adaptive immune system






Molecular and structural immunologyIRAK

Molecular and structural techniques play a major role in the understanding of immunological processes at the molecular level







Transplantationconfocal imaging of bladder dendritic cells

Understanding and minimising transplant rejection

The new Jeffrey Cheah Biomedical Centre - CITIID

See the home of CITIID being built in this fantastic time-lapse video. From basement to water tight in 17 months. The Jeffrey Cheah Bimedical Centre is now complete and home to the Cambridge Immunology Network Coordinator.


‘Fibroblast’ has been developed from a conversation between Harold Offeh and Dr Alice Denton, a scientist based at the Babraham Institute and a member of the Cambridge Immunology Network. Offeh was particularly interested in the character and roles played by particular cells in the immune system, as well as the immune system’s role as a primary source of protection and care. The film takes as a starting point microscopic images of broblast cells, an area of research for Dr Denton.

FCEs provide interdisciplinary training programmes for students, fellows and continuing education physicians through FOCIS assisted opportunities

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