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Cambridge Immunology Network

 

Clare Bryant is Professor of Innate Immunity in the Departments of Medicine and Veterinary Medicine.  She graduated in Biochemistry and Physiology in Southampton University before training as a vet at the Royal Veterinary College in London.  She was funded by the Wellcome Trust for her PhD (in London) before moving to the William Harvey Research Institute for 4 years as a Wellcome postdoctoral fellow. She then moved to Cambridge as a Wellcome Trust Career Development Fellow where she is now Professor of Innate Immunity.  She has been on secondments in Genentech and GSK, has extensive collaborations with many pharmaceutical companies, is on the scientific advisory board of several biotech companies, has a drug discovery project with Apollo Therapeutics and helped found the natural product company Polypharmakos.  During the COVID-19 pandemic she founded, and still runs, the Inflammazoom international seminar series.  She was elected as a Fellow of the British Pharmacology Society in 2018, Fellow of the American Academy of Microbiology in 2023 and Fellow of the Learned Society of Wales in 2023.

Professor Clare Bryant

Automatic single cell image analysis to measure the translocation of the pro-inflammatory transcription factor Nuclear Factor kappa B into the nucleus and the accompanying expression of the cytokine tumor necrosis factor alpha over time after stimulation of cells with lipopolysaccharide. Macrophages are transduced to express green fluorescent protein-Rel A (a constituent of Nuclear Factor kappa B) and a tumor necrosis factor alpha promoter linked to mCherry (red)