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Cambridge Immunology Network



My current work which focuses,  among others, on Class III PI3K signalling in T cell biology, including its  involvement in relation to autophagy, endocytosis and immunological memory to  pathogens such as Listeria.


Key publications: 
Ktistakis NT, Manifava M, Schoenfelder P, Rotondo S. How phosphoinositide 3-phosphate controls growth downstream of amino acids and autophagy downstream of amino acid withdrawal.Biochem Soc Trans. 2012 Feb;40(1):37-43.

Walker S, Chandra P, Manifava M, Axe E, Ktistakis NT. Making autophagosomes: localized synthesis of phosphatidylinositol 3-phosphate holds the clue. Autophagy. 2008 Nov;4(8):1093-6.

Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol. 2008 Aug 25;182(4):685-701.

Dr Priya  Schoenfelder (née Chandra)
Not available for consultancy